The Ontario College of Pharmacists adopted the National Association of Pharmacy Regulatory Authorities (NAPRA) Model Standards for Pharmacy Compounding of Non-Sterile Preparations following approval at the December 2017 Board meeting. The standards apply to all pharmacy professionals in all practice settings that engage in non-sterile compounding in any capacity and are an important way to ensure patient safety and protect pharmacy personnel. The implementation of these standards occurred in three phases: Phase 1 “Assessing Risks and Gaps”, Phase 2 “Personnel Training and Quality Assurance”, and Phase 3 “Facilities and Equipment”.
Full implementation of all 3 phases of the standards was expected by January 1, 2022 for all pharmacies engaging in non-sterile compounding activities. For more information about the non-sterile compounding standards and their application in practice, please refer to resources listed below.
Resources
Ontario College of Pharmacists Resources
National Association of Pharmacy Regulatory Authorities (NAPRA) Resources
Risk Assessments
Sample Safety Data Sheet (SDS)
Master Formulation Records
The Ontario Pharmacists Association (OPA) provides this material to pharmacy professionals for informational purposes only and is intended to assist pharmacy professionals but does not replace professional judgment and responsibilities. It is provided without warranty of any kind by OPA and OPA assumes no responsibility for any errors, omissions or inaccuracies therein. The decision for use and application of this document is the responsibility of the user. OPA assumes no liability for such use and application or any resulting outcomes. It is the responsibility of the pharmacy professional to use professional judgment in evaluating this material in light of any relevant clinical or situational data. It is intended to supplement materials provided by regulatory authorities, and should there be any discrepancies, municipal, provincial, and federal laws, policies and guidelines shall prevail. This information is up to date as at the date of publication. Pharmacy professionals are encouraged to confirm information with additional resources.
Date created: October 29, 2020. Date Updated: January 6, 2026
